Cristiano Ronaldo could also miss the second-leg of Real Madrid's Champions League semi-final against Man City.
The Portuguese star missed last night's scoreless draw at the Etihad Stadium with a thigh injury and Spanish media are now reporting that he has been diagnosed with a muscle tear, which would make him a doubt for the return-leg in Madrid next week.
Marca state that he will undergo more tests to check his availability.
If Manchester City score once in the second leg, Real Madrid will need to score twice to overcome the away goal.
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