Ulster have called upon Ireland captain Rory Best and Paddy Jackson for their European Champions Cup meeting with Clermont in Kingspan Stadium.
Neither the hooker nor the out half played in last weeks bonus point win away to Cardiff in the Guinness Pro 12.
Tommy Bowe has been named on the wing while Irish international centres Luke Marshall and Stuart McCloskey form the centre pairing.
Iain Henderson and Chris Henry form two-thirds of the back-row alongside Sean Reidy.
Ulster are third in their pool after losing to Bordeaux Begles in their opener, before a narrow 19-18 home win over Exeter Chiefs.
Ulster starting XV: Piutau, Bowe, L Marshall, McCloskey, Ludik, Jackson, Pienaar; McCall, Best, Herbst, Browne, Diack, Henderson, C Henry, Reidy.
Replacements: Herring, Warwick, Ah You, Treadwell, Ross, P Marshall, Cave, Stockdale.
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