Irish lock James Ryan will face a race against time to be fit for Ireland's two remaining Six Nations games later this year.
Andy Farrell's side is due to take on Italy on 24 October and France a week later, to conclude the tournament that was postponed back in March due to the spread of Covid-19.
Leinster head coach Leo Cullen issued a squad update today and the 24-year-old is set to be out for up to three months.
He requires 10-12 weeks to recover from shoulder surgery.
Disappointing news today that @adamsbyrne and @JamesRyan126 have been ruled out for several weeks.
Get well soon, lads. 🔵👊
Full update: https://t.co/crcQBGHhXA#LeinsterRugby pic.twitter.com/3NqEDzqezN
— Leinster Rugby (@leinsterrugby) August 3, 2020
The update also revealed that Adam Byrne is set to be out of action for up to three months as well.
The 26-year-old winger has suffered a hamstring injury and is due to have a procedure on it this week.
This means both players will miss the Blues derby Pro-14 fixture against Munster at the Aviva Stadium on 22 August.
In good news from the province, prop Peter Dooley is expected to return to training in two weeks following a shoulder injury and Ireland flanker Dan Leavy is 'continuing to integrate gradually into rugby training after a significant multi-ligament knee injury'.
Download the brand new OffTheBall App in the Play Store & App Store right now! We've got you covered!
Subscribe to OffTheBall's YouTube channel for more videos, like us on Facebook or follow us on Twitter for the latest sporting news and content.