Sevens player Aoife Doyle will line out for Ireland's women's 15s team for the first time since 2015 this weekend.
The Munster winger has been named to start by head-coach Adam Griggs for their Six Nations clash with Scotland at Donnybrook this Sunday.
Gloucester's Ellen Murphy has been selected at out-half with Ciara Griffin captaining the team from the back-row.
"The preparation leading up to the tournament has been very good," Griggs told Irish Rugby.
"We’ve got a lot of work done through January as a squad and at this stage everyone is excited to get the Six Nations started and show the progress we've made.
"We’ve made no secret that last season’s results were not good enough and having a home game first up is the best possible way to start and put in a performance for ourselves and our home crowd.
"We want to make sure that Energia Park is a hard place for travelling teams to come and play so we must put our words into action and apply pressure from the very start.
"Scotland, first up, is a huge game for us. We are well aware what they can bring, and simply, we need to be on our game and deliver our best performance yet to get the tournament off to a winning start."
Ireland v Scotland: Lauren Delany (Firwood Waterloo/ IQ Rugby), Aoife Doyle (Railway Union/ Munster), Sene Naoupu (Old Belvedere/ Leinster), Michelle Claffey (Blackrock/ Leinster), Beibhinn Parsons (Ballinasloe/ Connacht), Ellen Murphy (Gloucester-Hartpury/ IQ Rugby), Kathryn Dane (Old Belvedere/ Ulster); Lindsay Peat (Railway Union/ Leinster), Cliodhna Moloney (Wasps/ IQ Rugby), Linda Djougang (Old Belvedere/ Leinster), Aoife McDermott (Railway Union/ Leinster), Nichola Fryday (Old Belvedere/ Connacht), Ciara Griffin (UL Bohemian/ Munster, Capt), Edel McMahon (Wasps/ Connacht / IQ Rugby), Anna Caplice (Harlequins/ IQ Rugby)
Replacements: Victoria Dabanovich O'Mahony (Old Belvedere/ Leinster), Laura Feely (Galwegians/ Connacht), Leah Lyons (Harlequins/ IQ Rugby), Ciara Cooney (Railway Union/ Leinster), Dorothy Wall (Railway Union/ Munster), Nicole Cronin (UL Bohemian / Munster), Claire Keohane (Railway Union/ Munster), Laura Sheehan (UL Bohemian/ Munster)
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